Invention Grant
- Patent Title: Processes for the synthesis of olanzapine
- Patent Title (中): 奥氮平合成方法
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Application No.: US11976978Application Date: 2007-10-30
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Publication No.: US07863442B2Publication Date: 2011-01-04
- Inventor: Kiran Kumar Kothakonda , Daqing Che , Bhaskar Reddy Guntoori
- Applicant: Kiran Kumar Kothakonda , Daqing Che , Bhaskar Reddy Guntoori
- Applicant Address: CA Brantford
- Assignee: Apotex Pharmachem Inc.
- Current Assignee: Apotex Pharmachem Inc.
- Current Assignee Address: CA Brantford
- Priority: CA2593407 20070622
- Main IPC: C07D495/02
- IPC: C07D495/02
Abstract:
There is provided a process for the preparation of olanzapine comprising: i) reacting 4-amino-2-methyl-10H-thieno-[2,3-b][1,5]benzodiazepine and N-methylpiperazine in a C1 to C4 alcoholic solvent or mixture thereof at suitable temperature and for a suitable time, ii) cooling the reaction mixture, and iii) isolating the precipitated olanzapine.
Public/Granted literature
- US20080319189A1 Processes for the synthesis of olanzapine Public/Granted day:2008-12-25
Information query
