A pressurizable chamber device or containment vessel and method of use thereof. The device or vessel includes two chamber portions, a lid portion and a base portion, drawn to one another via a nut portion. The lid and base portions each include concave surfaces that matingly fit together, such that an internal chamber is formed when these portions are fit together. The lid and base portions each include a flange having a groove therein, such that a flexible seal element is fittable into the groove. The lid and base portions include features to matingly engage the nut portion, such that engagement thereamong draws the lid portion and the base portion toward one another, tightly sealing the formed internal chamber. A pressure, such as a resin pressure that may be precisely regulated, may then be applied, for example, to a mold contained within the formed and tightly sealed chamber.