发明授权
- 专利标题： Chimeral polypeptide composition for cross-placenta delivery
- 专利标题（中）： 用于跨胎盘递送的多肽组合物
-
申请号： US11769693申请日： 2007-06-27
-
公开(公告)号： US07871624B2公开(公告)日： 2011-01-18
- 发明人: Jeffrey H. Grubb , William S. Sly
- 申请人： Jeffrey H. Grubb , William S. Sly
- 申请人地址： US MO St. Louis
- 专利权人： Saint Louis University
- 当前专利权人： Saint Louis University
- 当前专利权人地址： US MO St. Louis
- 代理机构： Husch Blackwell LLP
- 代理商 Mark E. Stallion
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The invention is directed to chimeral fusion proteins having an IgG1 antibody Fc portion and a lysosomal storage enzyme, particularly a Fc-GUS fusion protein useful in treating Sly's disease in an embryo or fetus. The invention is also directed to methods of treating in born errors of metabolism, particularly Sly's disease, in a fetus by delivering to a pregnant mother a Fc-MPS emzyme fusion protein.
公开/授权文献
- US20080025995A1 Cross-Placenta Delivery System 公开/授权日：2008-01-31
信息查询
