Invention Grant
US07871816B2 Vector for anti-HPV vaccine and transformed microorganism by the vector
有权
载体用于抗HPV疫苗和转化的微生物载体
- Patent Title: Vector for anti-HPV vaccine and transformed microorganism by the vector
- Patent Title (中): 载体用于抗HPV疫苗和转化的微生物载体
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Application No.: US11939546Application Date: 2007-11-13
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Publication No.: US07871816B2Publication Date: 2011-01-18
- Inventor: Moon-Hee Sung , Ha Ryoung Poo , Jong Soo Lee , Chang Min Jung , Seung Pyo Hong , Chul-Joong Kim , Sue-nie Park , Hyun-mi Pyo
- Applicant: Moon-Hee Sung , Ha Ryoung Poo , Jong Soo Lee , Chang Min Jung , Seung Pyo Hong , Chul-Joong Kim , Sue-nie Park , Hyun-mi Pyo
- Applicant Address: KR KR
- Assignee: Bioleaders Corporation,Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Bioleaders Corporation,Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR KR
- Agency: Intellectual Property/Technology Law
- Agent Kelly K. Reynolds; Steven J. Hultquist
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N15/00

Abstract:
Expression vectors that can efficiently produce virion capsid protein, tumor-associated protein of human papillomavirus on a microbial surface. Bacterial strains harboring such surface display vectors, and the use of the bacterial strains or their extracts or purified products as complex vaccines, are also described. The surface display vectors contain one or more than two genes selected from among pgsB, pgsC and pgsA, encoding a poly-χ-glutamic acid synthetase complex (pgsBCA) of a Bacillus sp. strain, and genes that encode virion capsid proteins, tumor-associated proteins of human papillomavirus. Methods for preparing the foregoing vectors, vaccines and transformed microorganisms are also described.
Public/Granted literature
- US20090117151A1 VECTOR FOR ANTI-HPV VACCINE AND TRANSFORMED MICROORGANISM BY THE VECTOR Public/Granted day:2009-05-07
Information query
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