Detecting a symbol of interest comprises despreading a received signal to obtain despread values corresponding to the symbol of interest and to one or more interfering symbols, combining the despread values to generate combined values for the symbol of interest and the interfering symbols, computing spreading waveform correlations between the spreading waveform for the symbol of interest and the spreading waveforms for the interfering symbols, computing interference rejection terms representing the interference present in the combined value for the symbol of interest attributable to the interfering symbols based on the spreading waveform correlations, and generating an estimate of the symbol of interest by combining the combined values with the interference rejection terms. The interference rejection terms are computed by scaling the spreading waveform correlations by corresponding signal powers and compensating the estimates for noise. This provides a robust interference model that avoids numerical problems associated with conventional joint detection.