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发明授权
US07880022B2 Method for separation and purification of 13-dehydroxybaccatin III and 10-deacetylpaclitaxel from taxans-containing materials 有权
13种脱羟基浆果赤霉素Ⅲ和10-脱乙酰紫杉醇分离纯化方法

Method for separation and purification of 13-dehydroxybaccatin III and 10-deacetylpaclitaxel from taxans-containing materials
摘要：
This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of paclitaxel and/or docetaxel that are anticancer agents.
摘要（中）：

本发明涉及一种从紫杉烷类物质如紫杉属物种中有效分离和纯化纯度高达90％或更高纯度，优选99.5％或更高纯度的13-脱羟基浆果赤霉素III和10-脱乙酰紫杉醇的方法， 因此获得的高纯度的13-脱羟基浆果赤霉素III和10-脱乙酰紫杉醇可以用作作为抗癌剂的紫杉醇和/或多西紫杉醇的半合成前体。

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