发明授权
US07880820B2 Systems and methods of all-optical fourier phase contrast imaging using dye doped liquid crystals
有权
使用染料掺杂液晶的全光学傅立叶相位成像的系统和方法
- 专利标题: Systems and methods of all-optical fourier phase contrast imaging using dye doped liquid crystals
- 专利标题(中): 使用染料掺杂液晶的全光学傅立叶相位成像的系统和方法
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申请号: US12795974申请日: 2010-06-08
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公开(公告)号: US07880820B2公开(公告)日: 2011-02-01
- 发明人: Chandra S. Yelleswarapu , Sri Rajeasekhar Kothapalli , D. V. Gopal L. N. Rao
- 申请人: Chandra S. Yelleswarapu , Sri Rajeasekhar Kothapalli , D. V. Gopal L. N. Rao
- 申请人地址: US MA Boston
- 专利权人: University of Massachusetts
- 当前专利权人: University of Massachusetts
- 当前专利权人地址: US MA Boston
- 代理机构: Wilmer Cutler Pickering Hale & Dorr LLP.
- 主分类号: G02F1/1335
- IPC分类号: G02F1/1335
摘要:
An assembly for converting a microscope into a phase contrast microscope includes a first optical Fourier element that Fourier transforms light from a coherent light source, a cell in the Fourier plane arranged to receive light from the first optical Fourier element, a second optical Fourier element arranged to receive light from the cell and inversely Fourier transform the received light to provide an image, an image sensor that detects the image and generates an electronic representation of the image, and an adaptor capable of coupling the first and second Fourier elements, the cell, and the image sensor to the microscope such that the first Fourier element Fourier transforms light collected by the microscope objective. The cell includes liquid crystal molecules having a phase transition temperature, wherein at temperatures exceeding the phase transition temperature, light transmitting through the liquid crystal molecules obtains a different phase than light transmitting through the liquid crystal molecules at temperatures below the phase transition temperature.
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