A method and apparatus for improving quality of a signal reproduced from a holographic storage medium in which a hologram is recorded by interference between a signal beam and a reference beam. The signal-quality improving method includes determining a page crosstalk value, which is caused in a page that is to be reproduced from the holographic storage medium by an adjacent page to the page that is to be reproduced, on the basis of on-pixel crosstalk values caused by a plurality of on-pixels of the adjacent page; and removing the determined page crosstalk value from a reproduced signal of the page that is to be reproduced. Since an interpage crosstalk that occurs when multiplexing recording in the holographic storage medium is calculated, and is removed from a reproduced signal, the quality of the reproduced signal can be improved.