发明授权
US07888020B2 Association of EDG5 polymorphism V286A with type II diabetes mellitus and venous thrombosis/pulmonary embolism and the use thereof
失效
EDG5多态性V286A与II型糖尿病和静脉血栓形成/肺栓塞的关系及其用途
- 专利标题： Association of EDG5 polymorphism V286A with type II diabetes mellitus and venous thrombosis/pulmonary embolism and the use thereof
- 专利标题（中）： EDG5多态性V286A与II型糖尿病和静脉血栓形成/肺栓塞的关系及其用途
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申请号： US11834998申请日： 2007-08-07
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公开(公告)号： US07888020B2公开(公告)日： 2011-02-15
- 发明人: Detlef Kozian , Evi Kostenis , Karl-Ernst Siegler , Martina Jacobs , Sylvain Ricard , Sandrine Mace , Jean-Francois Deleuze
- 申请人： Detlef Kozian , Evi Kostenis , Karl-Ernst Siegler , Martina Jacobs , Sylvain Ricard , Sandrine Mace , Jean-Francois Deleuze
- 申请人地址： DE Frankfurt am Main
- 专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人地址： DE Frankfurt am Main
- 代理商 J. Darrell Fontenot
- 优先权： EP02007879 20020409
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C07H21/04
摘要：
The present invention relates to a method of identifying an increase in risk for type II Diabetes mellitus, venous thrombosis, or pulmonary embolism in a subject, wherein the presence of an amino acid exchange at position 286 from valine (Val) to alanine (Ala) in the EDG5 protein in a biological sample taken from the subject.