发明授权
- 专利标题: Unnatural reactive amino acid genetic code additions
- 专利标题(中): 非天然的反应性氨基酸遗传密码添加
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申请号: US10826919申请日: 2004-04-16
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公开(公告)号: US07888063B2公开(公告)日: 2011-02-15
- 发明人: Alexander Deiters , T. Ashton Cropp , Jason W. Chin , J. Christopher Anderson , Peter G. Schultz
- 申请人: Alexander Deiters , T. Ashton Cropp , Jason W. Chin , J. Christopher Anderson , Peter G. Schultz
- 申请人地址: US CA La Jolla
- 专利权人: The Scripps Research Institute
- 当前专利权人: The Scripps Research Institute
- 当前专利权人地址: US CA La Jolla
- 代理机构: Quine Intellectual Property Law Group, P.C.
- 代理商 Stacy Landry; Christina Onufryk
- 主分类号: C12P21/06
- IPC分类号: C12P21/06 ; C12N9/16
摘要:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献
- US20040265952A1 Unnatural reactive amino acid genetic code additions 公开/授权日:2004-12-30
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