A Synchronous Positioning Frame Assembly Machine having a plurality of extension wings (48) arranged to precisely locate miter clamps (40) containing captive sliding rails (46) that create a secondary motion to connect small and large frame members. Artist canvas frames, picture frames and other rectangular or square frames such as mirror frames made from mitered members being joined with glue or other mechanical means are precisely brought together at right angles and in a flat plane. Rotary motion of a central rotating shaft (54) linked (50) to the sliding rails (46) positions the clamps (40). A mechanically or manually operated torque lever (56) with knob (58) provides the prime mover force that moves the clamps in a synchronized manner while applying a clamping force to hold the frame members A, B, C, D together with a ratchet (68) and pawl (88) stop for the required assembly time of glue cycle, manual or mechanical fasteners.