发明授权
- 专利标题: Recombinant infectious laryngotracheitis virus and uses thereof
- 专利标题(中): 重组感染性喉气管炎病毒及其用途
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申请号: US12363134申请日: 2009-01-30
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公开(公告)号: US07892564B2公开(公告)日: 2011-02-22
- 发明人: Martha A. Wild , Mark D. Cochran
- 申请人: Martha A. Wild , Mark D. Cochran
- 申请人地址: US NJ Summit
- 专利权人: Schering-Plough Animal Health Corp.
- 当前专利权人: Schering-Plough Animal Health Corp.
- 当前专利权人地址: US NJ Summit
- 主分类号: A61K39/245
- IPC分类号: A61K39/245
摘要:
The present invention provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the glycoprotein gG gene. This attenuated virus is useful as a vaccine against infectious laryngotracheitis virus.The present invention also provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the US2 gene, UL47-like gene, ORF4 gene or glycoprotein g60 gene.The present invention also provides a method for distinguishing chickens or other poultry vaccinated with a recombinant infectious laryngotracheitis virus which produces no glycoprotein gG from those infected with a naturally-occurring infectious laryngotracheitis virus.
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