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US07892773B2 Antibodies to human NK3-related prostate specific gene 1 proteins 失效
人NK3相关前列腺特异性基因1蛋白的抗体

Antibodies to human NK3-related prostate specific gene 1 proteins
摘要:
The present invention relates to a novel member of the NK family of homeobox genes. In particular, isolated nucleic acid molecules are provided encoding the human NK-3 prostate specific gene 1 (NKX3.1) protein. NKX3.1 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of NKX3.1 activity. Also provided are diagnostic methods for detecting prostate cancer and other cancers and therapeutic methods for prostate cancer and other cancers.
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