发明授权
US07892773B2 Antibodies to human NK3-related prostate specific gene 1 proteins
失效
人NK3相关前列腺特异性基因1蛋白的抗体
- 专利标题: Antibodies to human NK3-related prostate specific gene 1 proteins
- 专利标题(中): 人NK3相关前列腺特异性基因1蛋白的抗体
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申请号: US12059797申请日: 2008-03-31
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公开(公告)号: US07892773B2公开(公告)日: 2011-02-22
- 发明人: Wei-Wu He , Kenneth C. Carter
- 申请人: Wei-Wu He , Kenneth C. Carter
- 申请人地址: US MD Rockville
- 专利权人: Human Genome Sciences, Inc.
- 当前专利权人: Human Genome Sciences, Inc.
- 当前专利权人地址: US MD Rockville
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; C07K16/00 ; C07K7/08 ; C12N7/00 ; C12N5/10 ; C12N15/63 ; C07K14/00
摘要:
The present invention relates to a novel member of the NK family of homeobox genes. In particular, isolated nucleic acid molecules are provided encoding the human NK-3 prostate specific gene 1 (NKX3.1) protein. NKX3.1 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of NKX3.1 activity. Also provided are diagnostic methods for detecting prostate cancer and other cancers and therapeutic methods for prostate cancer and other cancers.
公开/授权文献
- US20080227127A1 Human NK3-Related Prostate Specific Gene-1 公开/授权日:2008-09-18
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