发明授权
- 专利标题: Hydrazone derivatives as kinase inhibitors
- 专利标题(中): 腙衍生物作为激酶抑制剂
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申请号: US11871472申请日: 2007-10-12
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公开(公告)号: US07893064B2公开(公告)日: 2011-02-22
- 发明人: Guozhang Xu , Lily Lee Searle , Shenlin Huang
- 申请人: Guozhang Xu , Lily Lee Searle , Shenlin Huang
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE
- 主分类号: C07D403/12
- IPC分类号: C07D403/12 ; A61K31/506
摘要:
The present invention is directed to novel bicyclic pyrimidine compounds of Formula (I) or a form or composition thereof as inhibitors of ATP-protein kinase interactions, wherein substituents on each side of the iminomethyl double bond in Formula (I) may be in the E or Z configuration; and wherein R1, R2, R3 and R4 are as defined herein.
公开/授权文献
- US20080114004A1 HYDRAZONE DERIVATIVES AS KINASE INHIBITORS 公开/授权日:2008-05-15