发明授权
- 专利标题: Methods and compositions for increasing solubility of azole drug compounds that are poorly soluble in water
- 专利标题(中): 提高难溶于水的唑类药物化合物溶解度的方法和组合物
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申请号: US12012413申请日: 2008-02-02
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公开(公告)号: US07893097B2公开(公告)日: 2011-02-22
- 发明人: Meidong Yang , Haigang Chen
- 申请人: Meidong Yang , Haigang Chen
- 申请人地址: US CA Petaluma
- 专利权人: Dow Pharmaceutical Sciences, Inc.
- 当前专利权人: Dow Pharmaceutical Sciences, Inc.
- 当前专利权人地址: US CA Petaluma
- 代理商 Howard Eisenberg, Esq.
- 主分类号: A61K31/425
- IPC分类号: A61K31/425 ; A61K31/42 ; A61K31/41 ; A61K31/415
摘要:
The combination of any two of a polyol, a polyol ether, and a low carbon organic alcohol provides a synergistic effect on the solubility of azole compounds, such as metronidazole, in aqueous fluid.
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