A method, system and computer program product for implementing general purpose PCRs with extended semantics (referred to herein as “ePCRs”) in a trusted, measured software module. The module is designed to run in one of a hypervisor context, an isolated partition, or under other isolated configurations. Because the software module is provided using trusted (measured) code, the software implementing the PCRs is able to run as a simple software process in the operating system (OS), as long as the software is first measured and logged. The software-implemented ePCRs are generated as needed to record specific measurements of the software and hardware elements on which an application depends, and the ePCRs are able to ignore other non-dependencies.