发明授权
- 专利标题: Nanoparticles for protein drug delivery
- 专利标题(中): 用于蛋白质药物递送的纳米颗粒
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申请号: US12455339申请日: 2009-06-01
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公开(公告)号: US07901666B1公开(公告)日: 2011-03-08
- 发明人: Hsing-Wen Sung , Hosheng Tu
- 申请人: Hsing-Wen Sung , Hosheng Tu
- 申请人地址: US CA Newport Beach TW Hsinchu
- 专利权人: GP Medical, Inc.,National Tsing Hua University
- 当前专利权人: GP Medical, Inc.,National Tsing Hua University
- 当前专利权人地址: US CA Newport Beach TW Hsinchu
- 主分类号: A61K51/00
- IPC分类号: A61K51/00 ; A61K9/50
摘要:
The invention discloses a pharmaceutical composition for treating a subject comprising two or more bioactive nanoparticles, thus treating the subject by co-administering the bioactive nanoparticles to the subject, wherein a first and a second bioactive nanoparticles comprise a shell portion that is dominated by positively charged chitosan, a core portion that contains negatively charged substrate, and at least a first bioactive agent in the first nanoparticle and a second bioactive agent in the second nanoparticle.
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