发明授权
US07901943B2 Materials and methods for controlling isotope effects during fractionation of analytes
有权
在分析物分解过程中控制同位素效应的材料和方法
- 专利标题： Materials and methods for controlling isotope effects during fractionation of analytes
- 专利标题（中）： 在分析物分解过程中控制同位素效应的材料和方法
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申请号： US12290784申请日： 2008-11-03
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公开(公告)号： US07901943B2公开(公告)日： 2011-03-08
- 发明人: Fred E. Regnier , Roujian Zhang
- 申请人： Fred E. Regnier , Roujian Zhang
- 申请人地址： US IN West Lafayette
- 专利权人： Purdue Research Foundation
- 当前专利权人： Purdue Research Foundation
- 当前专利权人地址： US IN West Lafayette
- 代理机构： Mueting, Raasch & Gebhardt, P.A.
- 主分类号： G01N33/22
- IPC分类号： G01N33/22 ; A61K38/00 ; C07K1/00 ; C07K14/00 ; C07K17/00
摘要：
Compositions and methods for controlling or eliminating isotope effects during fractionation of chemically equivalent but isotopically distinct compounds. Isotope coding agents contain heavy isotopes other than deuterium. The invention facilitates intelligent data acquisition. After sample fractionation, isotope abundance ratios are calculated using mass spectrometry, and analytes of interest are identified in real time.
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