发明授权
- 专利标题： Computer software to assist in identifying SNPS with microarrays
- 专利标题（中）： 计算机软件帮助识别SNPS与微阵列
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申请号： US11043294申请日： 2005-01-26
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公开(公告)号： US07904250B2公开(公告)日： 2011-03-08
- 发明人: Michael Molla , Todd Richmond , Steven Smith , Thomas Albert
- 申请人： Michael Molla , Todd Richmond , Steven Smith , Thomas Albert
- 申请人地址： US DE Wilmington
- 专利权人： Roche Nimblegen, Inc.
- 当前专利权人： Roche Nimblegen, Inc.
- 当前专利权人地址： US DE Wilmington
- 代理机构： Quarles & Brady LLP
- 主分类号： G01N33/50
- IPC分类号： G01N33/50
摘要：
The present invention is a method to assist in the identification of single nucleotide polymorphisms (SNP) from microarray hybridization data. Data from hybridization protocols run on microarrays often have variations in the data resulting from variations in hybridization conditions and efficiencies and variations in optical intensities. An algorithm is described to screen the results to identify those data points most likely to be real SNPs as opposed to variations in the hybridization or sensing data.
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