发明授权
US07910575B2 Prophylactic or therapeutic agents for allergic ophthalmic diseases or allergic nasal diseases, comprising tricyclic triazolobenzazepine derivative
失效
过敏性眼科疾病或过敏性鼻疾病的预防或治疗剂，包括三环三唑并苯并吖嗪衍生物
- 专利标题： Prophylactic or therapeutic agents for allergic ophthalmic diseases or allergic nasal diseases, comprising tricyclic triazolobenzazepine derivative
- 专利标题（中）： 过敏性眼科疾病或过敏性鼻疾病的预防或治疗剂，包括三环三唑并苯并吖嗪衍生物
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申请号： US12224594申请日： 2007-03-02
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公开(公告)号： US07910575B2公开(公告)日： 2011-03-22
- 发明人: Takashi Shishikura , Tsuneyoshi Inaba , Yukari Hoshina , Hirotomo Akabane , Mitsuhiro Uchida
- 申请人： Takashi Shishikura , Tsuneyoshi Inaba , Yukari Hoshina , Hirotomo Akabane , Mitsuhiro Uchida
- 申请人地址： JP Tokyo-To
- 专利权人： Meiji Seika Kaisha, Ltd.
- 当前专利权人： Meiji Seika Kaisha, Ltd.
- 当前专利权人地址： JP Tokyo-To
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JP2006-055706 20060302; JP2006-055711 20060302
- 国际申请： PCT/JP2007/054008 WO 20070302
- 国际公布： WO2007/100079 WO 20070907
- 主分类号： A01N43/00
- IPC分类号： A01N43/00 ; A01N43/04
摘要：
The present invention provides a pharmaceutical composition for use in the prophylaxis or treatment of allergic ophthalmic diseases or allergic nasal diseases, which comprises 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzazepine, 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzazepine or a pharmaceutically acceptable salt thereof. The pharmaceutical composition according to the present invention has few side effects, exerts strong prophylactic and therapeutic effects in the late phase exhibiting pharmaceutical resistance to conventional instillations, and can be used appropriately for topical applications.
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