发明授权
- 专利标题: Process for producing aminoacetyl pyrrolidine carbonitrile derivative and intermediate for production thereof
- 专利标题(中): 制备氨基乙酰基吡咯烷腈衍生物及其制备方法
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申请号: US12224849申请日: 2007-02-02
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公开(公告)号: US07915427B2公开(公告)日: 2011-03-29
- 发明人: Yoshikazu Asahina , Yasumichi Fukuda , Futoshi Shiga
- 申请人: Yoshikazu Asahina , Yasumichi Fukuda , Futoshi Shiga
- 申请人地址: JP Tokyo
- 专利权人: Kyorin Pharmaceuticals Co., Ltd.
- 当前专利权人: Kyorin Pharmaceuticals Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2006-062548 20060308
- 国际申请: PCT/JP2007/051768 WO 20070202
- 国际公布: WO2007/102286 WO 20070913
- 主分类号: C07D207/04
- IPC分类号: C07D207/04
摘要:
Novel intermediates for the production of aminoacetyl pyrrolidine carbonitrile derivatives ensure the safe and efficient production of the compounds. Specifically, the present invention provides a sulfonyloxyacetyl pyrrolidine derivative, represented by the following formula:(Chemical Formula 1) (wherein R1 is a substituted or unsubstituted C1-C6 alkyl group, a substituted or unsubstituted C3-C6 cycloalkyl group, a substituted or unsubstituted arylmethyl group, a substituted or unsubstituted aromatic hydrocarbon, a substituted or unsubstituted aromatic heterocyclic ring or a substituted or unsubstituted aliphatic heterocyclic ring; R2 is CONH2 or CN; and X is CH2, CHF or CF2.)
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