发明授权
- 专利标题: ZA loops of bromodomains
- 专利标题(中): 溴结构域的ZA环
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申请号: US09510314申请日: 2000-02-22
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公开(公告)号: US07919276B1公开(公告)日: 2011-04-05
- 发明人: Ming-Ming Zhou , Aneel K. Aggarwal
- 申请人: Ming-Ming Zhou , Aneel K. Aggarwal
- 申请人地址: US NY New York
- 专利权人: Mount Sinai School of Medicine
- 当前专利权人: Mount Sinai School of Medicine
- 当前专利权人地址: US NY New York
- 代理机构: Klauber & Jackson LLC
- 主分类号: C12P19/34
- IPC分类号: C12P19/34
摘要:
The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides a binding partner for the bromodomain. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.
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