发明授权
- 专利标题： Methods and compounds for controlled release of recombinant parvovirus vectors
- 专利标题（中）： 控释重组细小病毒载体的方法和化合物
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申请号： US11697194申请日： 2007-04-05
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公开(公告)号： US07923436B2公开(公告)日： 2011-04-12
- 发明人: Paul E. Monahan , Richard Jude Samulski , Joseph E. Rabinowitz
- 申请人： Paul E. Monahan , Richard Jude Samulski , Joseph E. Rabinowitz
- 申请人地址： US NC Chapel Hill
- 专利权人： University of North Carolina - Chapel Hill
- 当前专利权人： University of North Carolina - Chapel Hill
- 当前专利权人地址： US NC Chapel Hill
- 代理机构： Myers Bigel Sibley & Sajovec, P.A.
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K39/23
摘要：
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).
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