The present invention relates to a musical pillow. The music pillow includes a body, a pillow core defining a first receiving cavity corresponding to a users' head, and a music player device. The body includes a first base, and two sidewalls extending from two opposite sides of the first base. Two free ends of the two sidewalls face each other to define a body opening therebetween. The first base and the two sidewalls cooperatively define a receiving space. The pillow core is received in the receiving space, while the first receiving cavity is communicated with the body opening. The music player device includes two speakers positioned on the sidewalls respectively and a playing unit positioned in the first base. The speakers are electrically connected to the playing unit.