- 专利标题： Internalizing anti-CD74 antibodies and methods of use
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申请号： US12794823申请日： 2010-06-07
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公开(公告)号： US07931903B2公开(公告)日： 2011-04-26
- 发明人: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人： Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人地址： US NJ Morris Plains
- 专利权人： Immunomedics, Inc.
- 当前专利权人： Immunomedics, Inc.
- 当前专利权人地址： US NJ Morris Plains
- 代理商 Richard A. Nakashima
- 主分类号： A61K39/395
- IPC分类号： A61K39/395
摘要：
The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
公开/授权文献
- US20100266497A1 Internalizing Anti-CD74 Antibodies and Methods of Use 公开/授权日：2010-10-21
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