发明授权
- 专利标题: Modulation of MUC1 activity
- 专利标题(中): 调节MUC1活性
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申请号: US11816402申请日: 2006-02-14
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公开(公告)号: US07931904B2公开(公告)日: 2011-04-26
- 发明人: Donald W. Kufe
- 申请人: Donald W. Kufe
- 申请人地址: US MA Boston
- 专利权人: Dana Farber Cancer Institute, Inc.
- 当前专利权人: Dana Farber Cancer Institute, Inc.
- 当前专利权人地址: US MA Boston
- 代理机构: Fulbright & Jaworski
- 国际申请: PCT/US2006/005239 WO 20060214
- 国际公布: WO2006/088906 WO 20060824
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K39/38 ; A61K39/385 ; A61K38/00 ; A61P31/00
摘要:
The invention provides methods of identifying and making compounds that inhibit the interaction between MUC1 and either p53 or TBP. Also embraced by the invention are in vivo and in vitro methods of inhibiting such an interaction and of inhibiting the expression of MUC1 by a cell.
公开/授权文献
- US20080286264A1 Modulation of Muc1 Activity 公开/授权日:2008-11-20
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