发明授权
US07932248B2 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
失效
1H-吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑和色酮及其制备和用途
- 专利标题： 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
- 专利标题（中）： 1H-吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑和色酮及其制备和用途
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申请号： US11594993申请日： 2006-11-09
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公开(公告)号： US07932248B2公开(公告)日： 2011-04-26
- 发明人: Richard Schumacher , Jianguo Ma , Brian Herbert , Mihaela Diana Danca , Wenge Xie , Truc Minh Nguyen , Ashok Tehim
- 申请人： Richard Schumacher , Jianguo Ma , Brian Herbert , Mihaela Diana Danca , Wenge Xie , Truc Minh Nguyen , Ashok Tehim
- 申请人地址： US NJ Montvale
- 专利权人： Memory Pharmaceuticals Corporation
- 当前专利权人： Memory Pharmaceuticals Corporation
- 当前专利权人地址： US NJ Montvale
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 主分类号： A61P25/28
- IPC分类号： A61P25/28 ; A61K31/551 ; C07D487/08
摘要：
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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