An apparatus for detecting a biomolecule bonding using a radio frequency (RF) wireless energy transmission and a method thereof are disclosed. The method includes transmitting RF energy to a sensor module having one or more probe biomolecules immobilized thereon, and determining a first energy charging time of the sensor module, the first energy charging time representing the amount of time for the sensor to be completely charged by the transmitted RF energy, prior to mixing of the one or more probe biomolecules with one or more target sample biomolecules. A second energy charging time of the sensor module is determined, the second energy charging time representing the amount of time for the sensor to be completely charged by the transmitted RF energy, following mixing of the one or more probe biomolecules with one or more target biomolecule sample. A determination of whether biomolecule bonding has occurred is based on a variation of the first and second energy charging times.