发明授权
US07935793B2 Treatment of inflammatory bowel diseases with anti-IP-10 antibodies
有权
用抗IP-10抗体治疗炎症性肠病
- 专利标题： Treatment of inflammatory bowel diseases with anti-IP-10 antibodies
- 专利标题（中）： 用抗IP-10抗体治疗炎症性肠病
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申请号： US10581468申请日： 2004-11-10
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公开(公告)号： US07935793B2公开(公告)日： 2011-05-03
- 发明人: Balaji Balasa , Naoya Tsurushita , Nicholas F. Landolfi
- 申请人： Balaji Balasa , Naoya Tsurushita , Nicholas F. Landolfi
- 申请人地址： US CA Redwood City
- 专利权人： Abbott Biotherapeutics Corp.
- 当前专利权人： Abbott Biotherapeutics Corp.
- 当前专利权人地址： US CA Redwood City
- 国际申请： PCT/US2004/037600 WO 20041110
- 国际公布： WO2005/060457 WO 20050707
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; A61K39/395
摘要：
The present invention is directed to high affinity anti-human IP-10 antibodies or antigen-binding fragments of these antibodies, including chimeric, humanized or fully human antibodies. The present invention is also directed to a method of reducing the severity of at least one symptom of an inflammatory bowel disease in a subject in need thereof comprising administering to said subject an effective amount of an antagonist of IP-10, including the antibodies or antibody fragments of the present invention.
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