A user-interactive display system for a vehicle includes an interior rearview mirror assembly, a portable hand-held device, and a display device. The portable hand-held device is operable to communicate a first signal to a vehicle-based receiver. A user input is actuatable so that a user can select an item from a listing of choices displayed by the display device, whereby the user-interactive display system (a) displays at the display device data associated with the selected item in response to the user-selection of the selected item from the listing of choices, and/or (b) audibly plays at an audio device of the vehicle data associated with the selected item in response to the user-selection of the selected item from the listing of choices.