Invention Grant
US07939547B2 Compounds and compositions as channel activating protease inhibitors
失效
化合物和组合物作为通道活化蛋白酶抑制剂
- Patent Title: Compounds and compositions as channel activating protease inhibitors
- Patent Title (中): 化合物和组合物作为通道活化蛋白酶抑制剂
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Application No.: US11749001Application Date: 2007-05-15
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Publication No.: US07939547B2Publication Date: 2011-05-10
- Inventor: David C. Tully , Arnab K. Chatterjee , Hank Michael James Petrassi , Badry Bursulaya , Glen Spraggon
- Applicant: David C. Tully , Arnab K. Chatterjee , Hank Michael James Petrassi , Badry Bursulaya , Glen Spraggon
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Emily Tongco Wu
- Main IPC: A61K31/454
- IPC: A61K31/454 ; C07D403/02
Abstract:
The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
Public/Granted literature
- US20070276002A1 Compounds and Compositions as Channel Activating Protease Inhibitors Public/Granted day:2007-11-29
Information query
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