Invention Grant
US07943365B2 Δ-5 desaturases and their use in making polyunsaturated fatty acids 有权
&Dgr; -5去饱和酶及其在制备多不饱和脂肪酸中的应用

Δ-5 desaturases and their use in making polyunsaturated fatty acids
Abstract:
The present invention relates to Δ5 desaturases, which have the ability to convert dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) to arachidonic acid (ARA; 20:4 ω-6) and/or eicosatetraenoic acid (ETA; 20:4 ω-3) to eicosapentaenoic acid (EPA; 20:5 ω-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ5 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ5 desaturases in oleaginous yeast are disclosed.
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