Invention Grant
US07943365B2 Δ-5 desaturases and their use in making polyunsaturated fatty acids
有权
&Dgr; -5去饱和酶及其在制备多不饱和脂肪酸中的应用
- Patent Title: Δ-5 desaturases and their use in making polyunsaturated fatty acids
- Patent Title (中): &Dgr; -5去饱和酶及其在制备多不饱和脂肪酸中的应用
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Application No.: US12111237Application Date: 2008-04-29
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Publication No.: US07943365B2Publication Date: 2011-05-17
- Inventor: Howard Glenn Damude , Quinn Qun Zhu
- Applicant: Howard Glenn Damude , Quinn Qun Zhu
- Applicant Address: US DE Wilmington
- Assignee: E.I. du Pont de Nemours and Company
- Current Assignee: E.I. du Pont de Nemours and Company
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N1/19
- IPC: C12N1/19 ; C12N1/15 ; C12N15/00

Abstract:
The present invention relates to Δ5 desaturases, which have the ability to convert dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) to arachidonic acid (ARA; 20:4 ω-6) and/or eicosatetraenoic acid (ETA; 20:4 ω-3) to eicosapentaenoic acid (EPA; 20:5 ω-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ5 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ5 desaturases in oleaginous yeast are disclosed.
Public/Granted literature
- US20080274521A1 DELTA-5 DESATURASES AND THEIR USE IN MAKING POLYUNSATURATED FATTY ACIDS Public/Granted day:2008-11-06
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