发明授权
- 专利标题: RNAi inhibition of alpha-ENaC expression
- 专利标题(中): RNAi抑制α-ENaC表达
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申请号: US12771470申请日: 2010-04-30
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公开(公告)号: US07943592B2公开(公告)日: 2011-05-17
- 发明人: Gino Van Heeke , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans Peter Vornlocher
- 申请人: Gino Van Heeke , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans Peter Vornlocher
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 优先权: EP07110376 20070615; EP07114265 20070813
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68
摘要:
The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.
公开/授权文献
- US20100210513A1 RNAi Inhibition of Alpha-ENaC Expression 公开/授权日:2010-08-19
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