A tool holder, in particular for a measuring sensor, with an interface to a spindle of a machine tool is proposed. The tool holder comprises, as seen from the interface for the spindle, a material portion which differs from the customary basic material of a tool holder in a lower coefficient of linear expansion α and/or in a lower heat conductivity λ. According to the invention, the material portion affords thermal decoupling between the tool-side portion of the tool holder and a tool received therein from the tool spindle for reducing a length change on account of an introduction of heat coming from a comparatively hot tool spindle.