发明授权
US07947686B2 Substituted pyrazolo[4,3-c]pyridine derivatives active as kinase inhibitors
有权
作为激酶抑制剂活性的取代的吡唑并[4,3-c]吡啶衍生物
- 专利标题: Substituted pyrazolo[4,3-c]pyridine derivatives active as kinase inhibitors
- 专利标题(中): 作为激酶抑制剂活性的取代的吡唑并[4,3-c]吡啶衍生物
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申请号: US12096979申请日: 2006-12-06
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公开(公告)号: US07947686B2公开(公告)日: 2011-05-24
- 发明人: Tiziano Bandiera , Andrea Lombardi Borgia , Paolo Polucci , Manuela Villa , Marcella Nesi , Mauro Angiolini , Mario Varasi
- 申请人: Tiziano Bandiera , Andrea Lombardi Borgia , Paolo Polucci , Manuela Villa , Marcella Nesi , Mauro Angiolini , Mario Varasi
- 申请人地址: IT Nerviano (MI)
- 专利权人: Nerviano Medical Sciences S.r.l.
- 当前专利权人: Nerviano Medical Sciences S.r.l.
- 当前专利权人地址: IT Nerviano (MI)
- 代理机构: Scully, Scott, Murphy and Presser, P.C.
- 优先权: EP05111959 20051212
- 国际申请: PCT/EP2006/069285 WO 20061206
- 国际公布: WO2007/068619 WO 20070621
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61K31/437 ; C07D401/14 ; C07D471/04
摘要:
Substituted pyrazolo[4,3-c]pyridine derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a dysregulated protein kinase activity, like cancer.
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