发明授权
US07947694B2 Substituted pyrazolo[3,4-D]pyrimidines as cell cycle kinase inhibitors
有权
取代的吡唑并[3,4-D]嘧啶作为细胞周期激酶抑制剂
- 专利标题: Substituted pyrazolo[3,4-D]pyrimidines as cell cycle kinase inhibitors
- 专利标题(中): 取代的吡唑并[3,4-D]嘧啶作为细胞周期激酶抑制剂
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申请号: US11813654申请日: 2006-01-09
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公开(公告)号: US07947694B2公开(公告)日: 2011-05-24
- 发明人: Eddy Jean Edgard Freyne , Jean Fernand Armand Lacrampe , Timothy Pietro Suren Perera , Peter Ten Holte , Yannick Aimé Eddy Ligny , Delphine Yvonne Raymonde Lardeau , Tom Lavrijssen
- 申请人: Eddy Jean Edgard Freyne , Jean Fernand Armand Lacrampe , Timothy Pietro Suren Perera , Peter Ten Holte , Yannick Aimé Eddy Ligny , Delphine Yvonne Raymonde Lardeau , Tom Lavrijssen
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE
- 优先权: EP05100215 20050114
- 国际申请: PCT/EP2006/050096 WO 20060109
- 国际公布: WO2006/074984 WO 20060720
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/519 ; A61P35/00
摘要:
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, X1 and X2 have defined meanings, having cell cycle kinase inhibiting enzymatic activity, their preparation, compositions containing them and their use as a medicine.
公开/授权文献
- US20080039477A1 Pyrazolopyrimidines as Cell Cycle Kinase Inhibitors 公开/授权日:2008-02-14