Invention Grant
US07947834B2 Substituted quinoxalines, their preparation and their therapeutical use as 11βHSD1 modulators
有权
取代喹喔啉，其制备及其治疗用途为11＆amp; HSD1调节剂
- Patent Title: Substituted quinoxalines, their preparation and their therapeutical use as 11βHSD1 modulators
- Patent Title (中): 取代喹喔啉，其制备及其治疗用途为11＆amp; HSD1调节剂
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Application No.: US12337967Application Date: 2008-12-18
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Publication No.: US07947834B2Publication Date: 2011-05-24
- Inventor: Alain Braun , Patrick Mougenot , Claudie Namane , Eric Nicolai , Francois Pacquet , Christophe Philippo , Olivier Venier , Olivier Crespin , Cecile Pascal , Michel Aletru , Stefan Gussregen
- Applicant: Alain Braun , Patrick Mougenot , Claudie Namane , Eric Nicolai , Francois Pacquet , Christophe Philippo , Olivier Venier , Olivier Crespin , Cecile Pascal , Michel Aletru , Stefan Gussregen
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent Jiang Lin, Esq.
- Priority: FR0605786 20060627; FR0611239 20061222
- Main IPC: C07D241/36
- IPC: C07D241/36
Abstract:
The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11β-HSD1 is involved.
Public/Granted literature
- US20090176775A1 DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE Public/Granted day:2009-07-09
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