Invention Grant
US07947850B2 Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
失效
制备3,4-二取代 - 噻唑烷-2-酮的方法
- Patent Title: Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
- Patent Title (中): 制备3,4-二取代 - 噻唑烷-2-酮的方法
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Application No.: US12182918Application Date: 2008-07-30
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Publication No.: US07947850B2Publication Date: 2011-05-24
- Inventor: Jonathan B. DeCamp , Paul S. Watson , Jin She
- Applicant: Jonathan B. DeCamp , Paul S. Watson , Jin She
- Applicant Address: US NC Durham
- Assignee: Inspire Pharmaceuticals, Inc.
- Current Assignee: Inspire Pharmaceuticals, Inc.
- Current Assignee Address: US NC Durham
- Agency: Perkins Coie LLP
- Agent Viola T. Kung
- Main IPC: C07C323/58
- IPC: C07C323/58
Abstract:
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
Public/Granted literature
- US20080287683A1 PROCESS FOR THE PREPARATION OF 3,4-DISUBSTITUTED-THIAZOLIDIN-2-ONES Public/Granted day:2008-11-20
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