发明授权
US07947850B2 Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
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制备3,4-二取代 - 噻唑烷-2-酮的方法
- 专利标题： Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
- 专利标题（中）： 制备3,4-二取代 - 噻唑烷-2-酮的方法
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申请号： US12182918申请日： 2008-07-30
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公开(公告)号： US07947850B2公开(公告)日： 2011-05-24
- 发明人: Jonathan B. DeCamp , Paul S. Watson , Jin She
- 申请人： Jonathan B. DeCamp , Paul S. Watson , Jin She
- 申请人地址： US NC Durham
- 专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人地址： US NC Durham
- 代理机构： Perkins Coie LLP
- 代理商 Viola T. Kung
- 主分类号： C07C323/58
- IPC分类号： C07C323/58
摘要：
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
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