Invention Grant
- Patent Title: Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
- Patent Title (中): 用精氨酸剥夺治疗人类恶性肿瘤的药物制剂及方法
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Application No.: US10518223Application Date: 2003-06-20
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Publication No.: US07951366B2Publication Date: 2011-05-31
- Inventor: Ning Man Cheng , Yun Chung Leung , Wai Hung Lo
- Applicant: Ning Man Cheng , Yun Chung Leung , Wai Hung Lo
- Applicant Address: HK Central
- Assignee: Bio-Cancer Treatment International Limited
- Current Assignee: Bio-Cancer Treatment International Limited
- Current Assignee Address: HK Central
- Agency: Foley & Lardner LLP
- Priority: WOPCT/CN02/00635 20020909
- International Application: PCT/GB03/02665 WO 20030620
- International Announcement: WO04/000349 WO 20031231
- Main IPC: A61K38/46
- IPC: A61K38/46 ; C12N9/96 ; C12N9/14 ; C12N9/78 ; C12P21/06 ; C07H21/04
Abstract:
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
Public/Granted literature
- US20050244398A1 Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation Public/Granted day:2005-11-03
Information query
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