发明授权
- 专利标题： Protein stabilization formulations
- 专利标题（中）： 蛋白质稳定配方
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申请号： US11950127申请日： 2007-12-04
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公开(公告)号： US07956028B2公开(公告)日： 2011-06-07
- 发明人: Venkata R. Garigapati , Dongling Su , Rehan Khanzada , Steven J. Sawamura
- 申请人： Venkata R. Garigapati , Dongling Su , Rehan Khanzada , Steven J. Sawamura
- 申请人地址： US MA Raynham
- 专利权人： Johnson & Johnson Regenerative Therapeutics, LLC
- 当前专利权人： Johnson & Johnson Regenerative Therapeutics, LLC
- 当前专利权人地址： US MA Raynham
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/18 ; C07K14/00 ; C07K14/435 ; C07K14/46 ; C07K14/47 ; C07K14/475 ; C07K14/51
摘要：
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
公开/授权文献
- US20080147077A1 Protein stabilization formulations 公开/授权日：2008-06-19
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