发明授权
US07956077B2 2-{-3,′2-(phenyl)-oxazol-4-ylmethoxyl-cyclohexyl methoxy}-propionic acid derivatives used as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes
有权
用作治疗高脂血症和糖尿病的过氧化物酶体增殖物激活受体（PPAR）配体的2 - { - 3，“2-（苯基） - 恶唑-4-基甲氧基] - 环己基甲氧基} - 丙酸衍生物
- 专利标题： 2-{-3,′2-(phenyl)-oxazol-4-ylmethoxyl-cyclohexyl methoxy}-propionic acid derivatives used as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes
- 专利标题（中）： 用作治疗高脂血症和糖尿病的过氧化物酶体增殖物激活受体（PPAR）配体的2 - { - 3，“2-（苯基） - 恶唑-4-基甲氧基] - 环己基甲氧基} - 丙酸衍生物
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申请号： US11671673申请日： 2007-02-06
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公开(公告)号： US07956077B2公开(公告)日： 2011-06-07
- 发明人: Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- 申请人： Heiner Glombik , Christian Stapper , Eugen Falk , Stefanie Keil , Hans-Ludwig Schaefer , Wolfgang Wendler , Stephanie Knieps
- 申请人地址： DE Frankfurt Am Main
- 专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人： Sanofi-Aventis Deutschland GmbH
- 当前专利权人地址： DE Frankfurt Am Main
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 优先权： DE102004039532 20040814
- 主分类号： A01N43/76
- IPC分类号： A01N43/76 ; C07D263/34
摘要：
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistence and the like comprising acetic acid derivatives with cyclohexylmethoxy substituents and their salts. Known as peroxisome proliferator-activated receptors (PPAR) agonists/antagonists, the invention relates to compounds of formula I wherein the various substituent R-groups are more specifically defined herein.
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