发明授权
US07956189B2 Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore
失效
5-（1-（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基-2-（三氟甲基）三氟甲磺酸盐，马来酸盐，甲苯磺酸盐，富马酸盐和草酸盐 ）-5-喹啉] -4-氧杂二甲酰胺及其制备方法
![Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore](/docs/US/2011-06-07/US07956189B2/abs.jpg.600x600.jpg)
- 专利标题： Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore
- 专利标题（中）： 5-（1-（S） - 氨基-2-羟乙基）-N - [（2,4-二氟苯基） - 甲基] -2- [8-甲氧基-2-（三氟甲基）三氟甲磺酸盐，马来酸盐，甲苯磺酸盐，富马酸盐和草酸盐 ）-5-喹啉] -4-氧杂二甲酰胺及其制备方法
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申请号： US11891351申请日： 2007-08-10
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公开(公告)号： US07956189B2公开(公告)日： 2011-06-07
- 发明人: Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
- 申请人： Xiaoming Chen , Xiao Chen , Jianguo Yin , Xiaoyong Fu , David J. Blythin , Rongze Kuang , Ho-Jane Shue , Scott Trzaska , Chee-Wah Tang , Vincenzo Liotta , Zaher Shabani
- 申请人地址： US NJ Kenilworth
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： US NJ Kenilworth
- 代理商 Patricia A. Shatynski; Valerie J. Camara
- 主分类号： C07D215/38
- IPC分类号： C07D215/38
![Maleate, tosylate, fumarate and oxalate salts of 5-(1-(S)-amino-2-hydroxyethyl)-N-[(2,4-difluorophenyl)-methy]-2-[8-methoxy-2-(triflouromethy)-5-quinoline]-4-oxazolecarboxamide and preparation process therefore](/abs-image/US/2011/06/07/US07956189B2/abs.jpg.150x150.jpg)
摘要：
Disclosed are maleate, tosylate, fumarate, and oxalate salts of the compound 5-(1(S)-Amino-2-Hydroxyethyl)-N-[(2,4-Difluorophenyl)-Methyl]-2-[8-Methoxy-2-(Trifluoromethyl)-5-Quinoline]-4-Oxazolecarboxamide, represented by Formula I, and methods of preparing the same.