发明授权
US07964187B2 Sensitization of chemotherapeutic agent resistant neoplastic cells with a virus
有权
具有病毒的抗化学药物抗肿瘤细胞的致敏作用
- 专利标题: Sensitization of chemotherapeutic agent resistant neoplastic cells with a virus
- 专利标题(中): 具有病毒的抗化学药物抗肿瘤细胞的致敏作用
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申请号: US12555453申请日: 2009-09-08
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公开(公告)号: US07964187B2公开(公告)日: 2011-06-21
- 发明人: Matthew C. Coffey , Bradley G. Thompson
- 申请人: Matthew C. Coffey , Bradley G. Thompson
- 申请人地址: CA Calgary, Alberta
- 专利权人: Oncolytics Biotech Inc.
- 当前专利权人: Oncolytics Biotech Inc.
- 当前专利权人地址: CA Calgary, Alberta
- 代理机构: McKeon Meunier Carlin & Curfman, LLC
- 主分类号: A61K39/15
- IPC分类号: A61K39/15 ; C12N15/63
摘要:
The present invention relates to a method of increasing the sensitivity of neoplastic cells to chemotherapeutic agents by using a virus, a method of treating proliferative disorders with a virus and chemotherapeutic agents, and a method for preventing a neoplasm from developing drug resistance to chemotherapeutic agents. The virus is preferably a reovirus.
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