发明授权
- 专利标题: Tricyclic compounds as modulators of TNF-α synthesis
- 专利标题(中): 三环化合物作为TNF-α合成的调节剂
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申请号: US12532861申请日: 2009-01-23
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公开(公告)号: US07964608B2公开(公告)日: 2011-06-21
- 发明人: Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew Kostura , Mustafa Guzel
- 申请人: Adnan M. M. Mjalli , Bapu Gaddam , Dharma Rao Polisetti , Matthew Kostura , Mustafa Guzel
- 申请人地址: US NC High Point
- 专利权人: High Point Pharmaceuticals, LLC
- 当前专利权人: High Point Pharmaceuticals, LLC
- 当前专利权人地址: US NC High Point
- 代理商 Robert S. Dailey
- 国际申请: PCT/US2009/031819 WO 20090123
- 国际公布: WO2009/094528 WO 20090730
- 主分类号: A01N43/54
- IPC分类号: A01N43/54 ; A61K31/505 ; C07D239/70 ; C07D471/00
摘要:
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.
公开/授权文献
- US20100190808A1 Tricyclic Compounds As Modulators of TNF-alpha Synthesis 公开/授权日:2010-07-29
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