Invention Grant
- Patent Title: Aryl alkyl sulfonamides as therapeutic agents for the treatment of bone conditions
- Patent Title (中): 芳基烷基磺酰胺作为治疗骨质的治疗剂
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Application No.: US11628084Application Date: 2005-05-23
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Publication No.: US07964643B2Publication Date: 2011-06-21
- Inventor: Stuart Hamilton Ralston , Iain Robert Greig , Aymen Ibrahim Idris Mohamed , Robert Jurgen Van 'T Hof
- Applicant: Stuart Hamilton Ralston , Iain Robert Greig , Aymen Ibrahim Idris Mohamed , Robert Jurgen Van 'T Hof
- Applicant Address: GB Aberdeen
- Assignee: The University Court of the University of Aberdeen
- Current Assignee: The University Court of the University of Aberdeen
- Current Assignee Address: GB Aberdeen
- Agency: Nixon & Vanderhye P.C.
- Priority: GB0412553.0 20040604
- International Application: PCT/GB2005/002043 WO 20050523
- International Announcement: WO2005/118528 WO 20051215
- Main IPC: A61K31/18
- IPC: A61K31/18 ; C07C311/00
Abstract:
The present invention pertains to compounds of the following formula (wherein RP, r, q, RN, Ralk, and Q are as defined herein) and compositions comprising those compounds. The compounds may be used to inhibit osteoclast survival, formation, and/or activity; to inhibit conditions mediated by osteoclasts and/or characterised by bone resorption; in the treatment of bone disorders such as osteoporosis, rheumatoid arthritis, cancer associated bone disease, Paget's disease; and/or in the treatment of conditions associated with inflammation or activation of the immune system.
Public/Granted literature
- US20080119555A1 Aryl Alkyl Sulfonamides As Therapeutic Agents For The Treatment Of Bone Conditions Public/Granted day:2008-05-22
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