A manual spray dispenser for dispensing a mixture of two compositions comprises a container having a first and second chamber and a single dispensing spray outlet for dispensing controlled amounts of liquids from each of the first and second chambers. At least one of the chambers has a separator in the form of a pouch for physically separating the contents of the container from an interior surface of the chamber. The first chamber can contain a first composition and the second chamber can contain a second composition having a reactive component that reacts with at least one compound upon contact or mixing. The dispenser further contains a dispensing system for simultaneously dispensing the first composition and the second composition from their respective first and second chambers, mixing the two compositions together, and dispensing a mixture of the two compositions from the container under pressure.