发明授权
US07968523B2 Method for inducing apoptosis using apoptosis-specific EIF5-A
失效
使用凋亡特异性EIF5-A诱导细胞凋亡的方法
- 专利标题： Method for inducing apoptosis using apoptosis-specific EIF5-A
- 专利标题（中）： 使用凋亡特异性EIF5-A诱导细胞凋亡的方法
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申请号： US10200148申请日： 2002-07-23
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公开(公告)号： US07968523B2公开(公告)日： 2011-06-28
- 发明人: Catherine Taylor , Tzann-Wei Wang , Larry Petrov , John C. Carlson , Richard Narayansingh , John E. Thompson , Dominic O. Cliche , Marianne Hopkins
- 申请人： Catherine Taylor , Tzann-Wei Wang , Larry Petrov , John C. Carlson , Richard Narayansingh , John E. Thompson , Dominic O. Cliche , Marianne Hopkins
- 申请人地址： US NJ New Brunswick
- 专利权人： Senesco Technologies, Inc.
- 当前专利权人： Senesco Technologies, Inc.
- 当前专利权人地址： US NJ New Brunswick
- 代理机构： Morgan, Lewis & Bockius LLP
- 主分类号： A61K48/00
- IPC分类号： A61K48/00
摘要：
The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, and antisense oligonucleotides and expression vectors of apoptosis-specific eIF-5A and DHS useful in such methods.
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