发明授权
US07968557B2 Substituted pyrrolo[2,3-2]pyrimidines as protein kinase inhibitors
有权
取代的吡咯并[2,3-2]嘧啶作为蛋白激酶抑制剂
- 专利标题: Substituted pyrrolo[2,3-2]pyrimidines as protein kinase inhibitors
- 专利标题(中): 取代的吡咯并[2,3-2]嘧啶作为蛋白激酶抑制剂
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申请号: US10589099申请日: 2005-02-14
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公开(公告)号: US07968557B2公开(公告)日: 2011-06-28
- 发明人: Ha-Soon Choi , Zhicheng Wang , Nathanael Schiander Gray , Xiang-ju Gu , Xiaohui He , Yun He , Tao Jiang , Yi Liu , Wendy Richmond , Taebo Sim , Kunyong Yang
- 申请人: Ha-Soon Choi , Zhicheng Wang , Nathanael Schiander Gray , Xiang-ju Gu , Xiaohui He , Yun He , Tao Jiang , Yi Liu , Wendy Richmond , Taebo Sim , Kunyong Yang
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理机构: Novartis AG
- 代理商 Scott W. Reid
- 国际申请: PCT/US2005/004630 WO 20050214
- 国际公布: WO2005/080393 WO 20050901
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P37/06
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the FAK, Abl, BCR-Abl, PDGF-R, c-Kit, NPM-ALK, Flt-3, JAK2 and c-Met kinases.
公开/授权文献
- US20070225306A1 Compounds and Compositions as Protein Kinase Inhibitors 公开/授权日:2007-09-27
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