发明授权
- 专利标题: Secondary amines as renin inhibitors
- 专利标题(中): 仲胺作为肾素抑制剂
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申请号: US12223597申请日: 2007-01-31
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公开(公告)号: US07968720B2公开(公告)日: 2011-06-28
- 发明人: Olivier Bezencon , Daniel Bur , Olivier Corminboeuf , Daniel Dube , Corinna Grisostomi , Dwight MacDonald , Dan McKay , David Powell , Lubos Remen , Sylvia Richard-Bildstein , John Scheigetz , Michel Therien , Thomas Weller
- 申请人: Olivier Bezencon , Daniel Bur , Olivier Corminboeuf , Daniel Dube , Corinna Grisostomi , Dwight MacDonald , Dan McKay , David Powell , Lubos Remen , Sylvia Richard-Bildstein , John Scheigetz , Michel Therien , Thomas Weller
- 申请人地址: CH Allschwil
- 专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人地址: CH Allschwil
- 代理机构: Hoxie & Associates LLC
- 优先权: WOPCT/IB2006/050356 20060202
- 国际申请: PCT/IB2007/050327 WO 20070131
- 国际公布: WO2007/088514 WO 20070809
- 主分类号: C07D221/02
- IPC分类号: C07D221/02 ; C07C211/00
摘要:
The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
公开/授权文献
- US20090176823A1 Secondary Amines as Renin Inhibitors 公开/授权日:2009-07-09