发明授权
- 专利标题： Compounds, their preparation and use
- 专利标题（中）： 化合物，其制备和用途
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申请号： US11579712申请日： 2005-05-03
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公开(公告)号： US07968723B2公开(公告)日： 2011-06-28
- 发明人: Miroslav Havranek , Per Sauerberg , Ingrid Pettersson , Pavel Pihera , Soren Ebdrup
- 申请人： Miroslav Havranek , Per Sauerberg , Ingrid Pettersson , Pavel Pihera , Soren Ebdrup
- 申请人地址： US NC High Point
- 专利权人： High Point Pharmaceuticals, LLC
- 当前专利权人： High Point Pharmaceuticals, LLC
- 当前专利权人地址： US NC High Point
- 代理商 Robert S. Dailey
- 优先权： DK200400719 20040505
- 国际申请： PCT/EP2005/052014 WO 20050503
- 国际公布： WO2005/105726 WO 20051110
- 主分类号： C07D213/00
- IPC分类号： C07D213/00 ; A01N43/78
摘要：
Novel compounds of the general formula (I), in which the variables are as defined in claim 1, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPARδ subtype, namely, type 1 diabetes, type 2 diabetes, dyslipidaemia, syndrome X (including the metabolic syndrome, i.e. impaired glucose tolerance, insulin resistance, hyper-triglyceridaemia and/or obesity), cardiovascular diseases (including atherosclerosis) and hypercholesterolaemia.
公开/授权文献
- US20090209588A1 Novel compounds, their preparation and use 公开/授权日：2009-08-20
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